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dnaI [2018-10-05 09:40:23]
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dnaI [2018-10-05 09:40:23]

primosome component (helicase loader), part of the [SW|replisome]
locus
BSU28980
pI
5.74
mw
35.96 kDa
protein length
311 aa Sequence Blast
gene length
933 bp Sequence Blast
function
[category|SW 3.1.1|DNA replication]
product
primosome component (helicase loader)
essential
yes
synonyms
ytxA,dnaY
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.1|DNA replication]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]

    • Gene

    Coordinates
    2,963,185 → 2,964,120

    Phenotypes of a mutant

  • essential [Pubmed|12682299]

    • The protein

    Structure

  • [PDB|2K7R] (N-terminal domain)
  • [PDB|4M4W] (the [protein|5CF09E089AA70A32F640CE0D33D1F05312AAE24D|DnaC]-[protein|AC1B507C6B1640E9BEA1F9F01628120F3680C976|DnaI]-[protein|F7B53E8AC92DAD15544C6208C2A5B41BABA73D6D|DnaG] complex) [Pubmed|24048025]

    • [SW|Localization]

  • cell membrane (according to Swiss-Prot), Cytoplasm (Homogeneous) [Pubmed|16479537] forms foci, close to oriC [Pubmed|10844689]

    • Expression and Regulation

    Operons

    genes
    [gene|2AEF6D56D884CA6A0BD50FABD27F405DC2B506C7|dnaB]-[gene|AC1B507C6B1640E9BEA1F9F01628120F3680C976|dnaI]-[gene|72A4458679EA1451FA3B63D44C3BE93ACA8B397F|ytxB]-[gene|3EE0D03469D893515CAA4961BF923BE3A6769535|ytxC]-[gene|3E1131CFA3EDEB3865638F09BE2F6B6ED2570BE2|thrS]
    description
    [Pubmed|22383849]
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    References

    Reviews

  • 22797751,28075389

    • Original publications

  • 19255093,10844689,12718886,11842108,20122408,16479537,19744498,19255093,19968790,11679082,24048025